This work is dedicated to the study and investigation of thermoxidation processes in crude oil and petroleum products. The study of thermoxidation processes in crude oil and petroleum products was carried out using various analytical techniques, including IR, NMR, UV, small-batch reactor, TGA, DSC, DTA, thermochemical luminescence and others. One of the key characteristics of crude oil and petroleum products is their thermo-oxidative stability. During thermoxidation, hydrocarbons in the oil oxidize in an oxygen-rich environment, forming undesirable compounds such as hydroperoxides, alcohols, ketones, and others. These changes lead to increased viscosity and alterations in the chemical and physical properties of the product. The hydroperoxides formed during the process play a critical role as free radical initiators, which accelerate oxidation reactions. At higher temperatures, these reactions can produce solid particles, resins, and even sediments. In engines, such sediments can disrupt the normal flow within the fuel system, leading to improper process management, engine damage, increased operational costs, reduced efficiency, and environmental pollution. Effective management of oxidation processes and the implementation of preventive measures are crucial to addressing environmental issues such as soil and water contamination. In the oil industry, it is essential to enhance the understanding and control of oxidation processes to meet both the increasing global demand and the tightening environmental regulations. This approach not only improves production efficiency but also ensures the protection of the environment