The present study examines biopolymer interaction with clayey sand and strength improvement with 0.5 to 2.5% of guar gum. From the experimental results, it is observed that a nominal amount of biopolymer increases the geotechnical properties of the soil. The biopolymer has a solid possibility to replace the traditional and conventional stabilisation techniques. Therefore, the performance of guar gum in soil stabilisation is determined by the response surface method. In this statistical analysis, unconfined compressive strength is predicted by taking biopolymer % and curing days as input parameters. Regarding pavement construction, resilient modulus is a significant parameter to consider. The resilient modulus of guar gum-treated soil is correlated with unconfined compression strength by linear regression analysis. The suggested optimization approach could be really helpful for designers and engineers by giving an estimate on the strength parameters before testing them, saving time and resources.