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Surrounding rocks of underground engineering are subjected to long-term seepage pressure, which can deteriorate the mechanical properties and cause serious disasters. In order to understand the impact of seepage pressure on the mechanical property of sandstone, uniaxial compression tests, P-wave velocity measurements, and nuclear magnetic resonance (NMR) tests were conducted on saturated sandstone samples with varied seepage pressures (i.e. 0 MPa, 3 MPa, 4 MPa, 5 MPa, 6 MPa, 7 MPa). The results demonstrate that the mechanical parameters (uniaxial compressive strength, peak strain, elastic modulus, and brittleness index), total energy, elastic strain energy, as well as elastic strain energy ratio, decrease with increasing seepage pressure, while the dissipation energy and dissipation energy ratio increase. Moreover, as seepage pressure increases, the micro-pores gradually transform into meso-pores and macro-pores. This increases the cumulative porosity of sandstone and decreases P-wave velocity. The numerical results indicate that as seepage pressure rises, the number of tensile cracks increases progressively, the angle range of microcracks is basically from 50 degrees-120 degrees to 80 degrees-100 degrees, and as a result, the failure mode transforms to the tensile-shear mixed failure mode. Finally, the effects of seepage pressure on mechanical properties were discussed. The results show that decrease in the effective stress and cohesion under the action of seepage pressure could lead to deterioration of strength behaviors of sandstone. (c) 2024 Institute of Rock and Soil Mechanics, Chinese Academy of Sciences. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/ licenses/by-nc-nd/4.0/).

来源平台：JOURNAL OF ROCK MECHANICS AND GEOTECHNICAL ENGINEERING