Deep excavations in urban areas may cause excessive ground deformations, leading to potential damage to the surrounding buildings. To prevent such problems, some techniques, such as the anchored wall systems, are used as a supporting method. This study, based on a large number of data produced by FE simulations and using the MARS approach, first presents a straightforward relation that can predict the maximum horizontal displacement of the anchored wall systems. Then, a simple predictive relation using MARS is established for developing a unique stiffness parameter. Finally, a novel design procedure based on the proposed MARS models, the stiffness parameter, geometric relationships, and recommendations from the FHWA is developed. By following this procedure, one can reasonably estimate the lengths of the anchors, their spacing, and tensile forces. Furthermore, the maximum horizontal displacement of the excavation wall can be accurately predicted and compared with the real value for better safety control of the construction procedure.