Gravity waves (GWs) have an important influence on global atmospheric circulation, energy balance and chemical composition distribution, the research of GWs is one of very important and hot problems in atmospheric physics. Most of the researches have focused on the temperature and wind fields disturbances induced by GWs, however on the disturbance of atmospheric chemical composition are less. And these researches are mainly study the chemical composition disturbances near the mesopause by theoretical and numerical simulation, and lack of observational studies of the chemical composition disturbances of throughout the middle and upper atmosphere. Therefore we will study the influence of gravity wave on the global distribution of atmospheric chemical composition. Firstly, using the long-term TIMED satellite data, we will observe and study the GWs influence on spatial and temporal distribution of middle and upper atmospheric chemical composition. This is one of the main objectives of this project. By comparing the distribution characteristics of all kinds of chemical compositions under the effect of GWs, we will reveal their different response to GWs, and clarify the change laws of middle and upper atmospheric GWs. Another goal of this project is to set up a middle and upper atmospheric GWs experience model based on research results of the variations of atmospheric parameter perturbations. This study will not only deepen the current understanding of the GWs propagation characteristics and physical mechanism, but also significantly improve the middle and upper atmospheric dynamics and chemical coupling model.